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KMID : 0604520190450030299
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Journal of the Society of Cosmetic Scientists of Korea
2019 Volume.45 No. 3 p.299 ~ p.306
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Anti-inflammatory and Wrinkle Improvement Effects of Peptides from Ginseng Berry Amino Acidic Complex
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Kang Sang-Moon
Park Chung
Park Chung
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Abstract
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Ginseng berry (GB) contains Ginsenoside Re and has anti-inflammatory and anti-wrinkle properties. In this study, TLC fractions 1, 2, and 4 of the ginseng berry amino acid complex were identified and analyzed by HPLC.
And identified a peptide (AP-1) by LC/MASS analysis of fraction 1. The anti-inflammatory activity was confirmed by investigating the inhibitory effect of AP-1 on NO production. In addition, collagen synthesis using procollagen type I C-peptide (PIP) ELISA kit was 50% higher effective than that of the control group. From these results, the peptide isolated from ginseng berry amino acid complex is considered to have anti-inflammatory and anti-wrinkle effect, and may be useful as an anti-inflammatory and anti-aging cosmetic raw material.
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KEYWORD
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Ginseng berry, peptide, anti-inflammatory, wrinkle improvement, anti-aging
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